Posts Tagged ‘research’

Greater Risk Of Hip Dislocation Awaits Patients With Rheumatoid Arthritis

Friday, May 3rd, 2013

Patients with a history of rheumatoid arthritis (RA) were found to be at greater a danger for hip dislocation following hip replacement surgery compared to those with osteoarthritis (OA), medical experts say, citing findings from the first systemic review assessing complications following total joint arthroplasty. Evidence has also been uncovered that points to the strong possibility that RA patients are more prone to infection after total knee replacement surgery than patients with OA.

The results of this study were featured online in Arthritis & Rheumatism, the medical journal for the American College of Rheumatology.

Among patients ranging in ages from 25 and above, the ACR considers OA to be the most common form of arthritis with as many as 27 million Americans having it compared to 1.3 million that have RA. Conventional practice has long held the assumption that the best means for treating end-stage arthritis of the hip and knee is through total joint replacement. Some experts believe that the success of this form of intervention is evident in the increasing number of joint replacement procedures being performed. Further studies are needed to research the effectiveness of joint replacement procedures and implants while simultaneously accounting for other factors that might influence the outcome of recovery, like, market pressures, patient’s age, gender, and use of support systems.

Some medical experts believe that joint arthroplasty is successful in treating disability and relieving the pain caused by hip or knee arthritis. While it is believed that complication rates following these procedures are low, there have been some reports of serious side effects which include infection, joint dislocation, bleeding, and even increased death rates.

Medical researchers conducted a detailed review of the literature on cases involving joint arthroplasty in order to assess the risk of side effects relating patients with OA and RA after joint replacement surgery. Reports between January 1990 and December 2011 were collated and all in all as many as 40 studies were analyzed and evaluated. The study population represented patients from the ages of 18 and older who have had hip or knee replacements and excluded patients who had replacement surgery brought about by fractures or cancer.

The study authors analyzed the previous literature which suggested a clear trend among RA patients to be more prone to hip dislocation from hip replacement surgery compared to patients with a history of OA. RA patients were also at greater risk for infection following total knee replacement surgery than OA patients. The study team found no difference in revision rate, 90-day mortality, or blood clot risk between the two patient groups. In summary, the medical study team has collated their findings but accept the need for further study to find the factors influencing the differences in joint replacement complication rate between OA and RA patients.

 

URL References:

news-medical.net/news/20121128/Patients-with-RA-more-likely-to-have-dislocation-following-hip-replacement-surgery.aspx

 

Rattan May Be Made Into New Bone Implants

Wednesday, April 3rd, 2013

Italian researchers are attempting to use nanotechnological techniques to formulate bone replacement implants composed of rattan, medical industry sources say. The research findings initially presented at the National Research Council of Italy will be published next in an forthcoming issue of the International Journal of Healthcare Technology and Management.

In the coming years, the cases involving osteoporosis, accidental injuries, osteoarthritis, bone cancer, and other diseases related to aging will be expected to increase in conjunction with the increasing percentage of the world’s elderly population. As people’s lifestyles change and lifespans extend to accommodate for the innovations in healthcare technology continue to progress. To learn more about osteoporosis, treatments, and updates, read more on the Fosamax class action lawsuit information center on http://www.fosamaxclassaction.us/femur-fractures/.

Based on some of the desirable biochemical properties in bone that the researchers were searching for they found that the microscopic structure of some wood were very similar to natural bone, such as, high strength, durability, and light-weight qualities found in their natural hierarchical organization. The researchers have already created prototypes of these implants using nanotechnology to transform rattan wood into hierarchically suitable implants. These biomimetic materials have natural qualities similar to natural bone, which is something that cannot be achieved by current plastic or metal alloy implants.

The main benefit of using rattan wood, according to the researchers, is how the hierarchical physical structure of rattan wood might be used as a scaffold for creating synthetic materials that may be used to replace lost or damaged bone. Further benefits from such materials includes load-bearing, which is a factor that has precluded the use of earlier biomimetic materials.

There are properties of wood that that would make the implants incompatible with humans and the process that removes is long and complex but the researchers maintain that the benefits are worth the effort. Making a synthetic carbon-based material that may be used to duplicate the skeletal bone structure which may also react with oxygen, calcium, and phosphate to make a porous material capable of chemically and mechanically mimicking bone is a potential breakthrough that is imperative for the good of mankind and the advancement of science. The key difference in the rattan based synthetic model is that the material is low-cost, low-weight, has very ideal biomechanics, is biocompatible, and can be integrated into existing bone better than that of conventional metal, ceramic, plastic, and even donor bone implants which makes this material better at assisting proper bone regeneration.

URL Reference:

news-medical.net/news/20121213/Researchers-use-nanotechnological-approach-to-transform-rattan-wood-into-implants.aspx

Taking Calcium Supplements No Longer Danger For Patients Heart Health

Monday, January 21st, 2013

A new research finding indicates that calcium supplements actually do not contribute to arterial hardening, experts claim, citing a new study that centered on 1,200 CT scans of men and women. Patients diagnosed with osteoporosis may use from this conclusion; particularly those who want to look for alternatives to osteoporosis treatment, such as, bisphosphonate related side-effects like the continuing Fosamax class action litigations.

Heart attacks brought about by arterial hardening was the main reason why previous expert studies advised against taking calcium supplements, which was the suspected cause.   This new research was posted on the American Journal of Ctritical Nuitrition by the efforts of the Framingham Offspring Study.

Experts claim that current clinical results have indicated no relationship between taking calcium supplements, whether short term or long term, and developing cardiovascular disease. They made the further conclusion that based on the data, they deferred to the recommendations of previous studies advocating for the use of calcium supplements as an acceptable treatment from osteoporosis since they posed no threat to cardiovascular health.

Elizabeth Samuelson and her researchers from the Harvard Medical School studied over 690 women and 588 men over the average age of 60. Intakes of dietary and supplemental calcium were assessed using a questionnaire and arterial calcification was monitored using a CT scan.

Their findings indicated that coronary artery calcification actually receded with increased calcium intake. It was also noted that the trend benefit was not too significant after adjusting for a number of other contributing factors, such as, age, BMI, and lifestyle factors.

The presence and severity of cardiovascular atherosclerosis necessitated its measurement by the study authors in order to gage how it related to other important factors in the study, such as, calcium intake, vascular calcification, vitamin D intake, prevalent coronary artery disease and kidney function. Cardiovascular thickening or atherosclerosis is an independent predictor of potential cardiovascular events.

The researchers concluded that, based on their finding’s, there was not enough evidence to support the assertion that coronary artery hardening was a result of significant detrimental effect from the intake of calcium supplements.

Besides supplements, other sources of dietary calcium include, dairy sources, dark green leafy vegetables, fruits, such as, banana’s, and certain forms of fish, like, wild salmon and sardines.

URL Reference:

nutraingredients.com/Research/Calcium-supplements-safe-for-heart-health-Harvard-study

Stem Cells: The Future Of Medical Research

Saturday, September 8th, 2012

Stem cell researchremainsone of the most researched and controversial scientific studies in the last decade,media reports say. As one of the most lucrative industries with a growing demand for services and one of the most visible sciences that is seen to benefit humanity, medical science in recent years has been forging ahead for years in innovation and advancement.

Stem cells are living cells found in all complex living organisms that can differentiate into specially diverse cell types which can renew by themselves to produce more stem cells. The potential for these cells to be used to replace damaged human tissue and even possibly create duplicate working human organs for failed ones such as, kidney’s pancreas, liver etc is great.

In order to enable the study and use of stem cells they must be harvested from human donors which makes them especially hard to come by. The controversy in this field of study stems from the harvesting techniques as well as the moral implications of being able to upset the natural order things by potentially being able to create not only newer and better organs but possibly new people. (human cloning,among others)

 

Gathering adult human stem cells is categorized into three autologous harvesting techniques. The first is bone marrow aspiration and another is by peripheral blood pheresis and liposuction of adipose tissue. Autologous harvesting is when the recipient is their donor and this is often the safest form of stem cell harvesting.

The most beneficial type of stem cells are the ones harvested from fertilized human zygotes called embryonic stem cells, which also happen be the most controversial. Human stem cell research benefits can be seen in duplicating and repairing damaged tissue with highly specific and stable cells. Of the two types of stem cells, embryonic is preferred over adult stem cells because the latter can only be used to grow specific tissue from the organs they were harvested from while embryonic stem cells can be cultured to grow just about anything.

At its heart, stem cell research is about regenerative medicine which believes that adult stem cells can be used to treat and cure many common chronic diseases that modern medical science has no permanent cure for. For example; Alzheimer’s, Parkinson’s,diabetestype 1, certain forms of cancer, spinal cord injury, heart and brain damage, wound healing, birth defects,and possibly even osteoporosis. More testing is required to determine the exact effects of these treatments on damaged tissue over time and any possible long-term side-effects but suffice to say medical experts say the sky is the virtual limit with what stem cells can be used to treat and cure over time.

One example of this form of treatment already being used recently is in contact lens with stem cells used to repair corneal damage and sight problems. One of the top Asian countries counted by media reports as being a frontrunner in the study of this very important research is the Philippines.

So, why does something so potentially beneficial engender so much animosity and mistrust? It could be people are simply resistant to change or are considerate of the moral implications of man supposedly “playing-god”. There are others who have mentioned that a primal fear is present which is tied to the fear of men feeding on his fellow man which may be the source of this fascination.

As long as medical science will continue to study this potentially life-changing treatment, so will the debate for its ethical and moral consideration, continue.

 

URL references:

business.inquirer.net/61629/ph-leads-way-to-stem-cell-therapy

allaboutpopularissues.org/pros-and-cons-of-stem-cell-research.htm

allaboutpopularissues.org/pros-and-cons-of-stem-cell-research.htm

Enticing Alpha Lipoic Acid Opinions

Sunday, July 18th, 2010

The list of probable alpha lipoic acid advantages is long, although damaging side effects are rare.

Acne is generally a sort of epidermis disease occurring at the sebaceous follicles on the skin. It normally appears within the face, neck and back. This then causes the follicles and its surrounding tissues to grow to be inflamed. It is a fantastic point to learn that a this sort of a compound as alpha lipoic acid for pimple may well hold a solution.

Getting To Know Acne There are two forms of acne, possibly inflammatory or non-inflammatory.

There are already several alpha lipoic acid clinical studies, pre clinical trials and laboratory studies. This is merely a brief review of all those studies.

First, just to become clear, here is usually a brief explanation in the distinction involving clinical and pre clinical studies.

Other scientific studies are deemed pre clinical, simply because they took location inside a laboratory setting utilizing both cell lines or animal models.

In the circumstance of small alpha lipoic acid medical research or single blind studies, research workers commonly suggest bigger a lot more manipulated studies. The alpha lipoic acid medical scientific tests which can be regarded as most scientifically sound are individuals that happen to be placebo manipulated and double blind.

A placebo managed research is one in which about 50 % with the participants receive an active westernunion texas ingredient and about 50 percent obtain an inactive material or “placebo”. Double blinding suggests that neither the individual getting the substance, nor the person “handing out the pills” knows and that is “real” and that is definitely not.

Double blind placebo managed scientific tests are particularly crucial when evaluating symptoms such as discomfort relief, but not so much in other cases. And in some situations medical scientific studies are basically impossible.

For example, alpha lipoic acid rewards that are already suggested by laboratory studies include things like the prevention of cancer.

Alpha lipoic acid clinical scientific tests have shown benefit to individuals who’ve undergone radiation and/or chemotherapy for your therapy of cancer.

Other laboratory scientific tests have indicated that alpha lipoic acid advantages may perhaps consist of the prevention of heart disease.

What Is Alpha Lipoic Acid? Tagged by some as the “universal” antioxidant, alpha lipoic acid is employed broadly for its power to cure and prevent several ailments by neutralizing totally free radicals in our bodies and safeguarding the cells from damage. Free radicals are substances that cause damage for the cells. Some common sources of free of charge radicals are fried foods, smoking, exhaust, and pollution.

In their opening statement research workers pointed out that ALA and l-carnitine are identified to cut down oxidative tension and enhance mitochondrial function. Their goal was to see what if any impact supplementation would have on individuals with coronary artery disease, higher blood pressure and metabolic syndrome.

Study participants were clients generic propecia buy with either coronary artery illness or metabolic syndrome. At the end in the eight week trial, those people participants getting ALA and acetyl-l-carnitine had significantly lower blood stress and elevated diameter within the brachial artery, the key blood vessel from the arm.

This study suggests that alpha lipoic acid advantages include things like stabilizing blood stress and improving blood flow and support the thought that kamagra cheap ALA supplements may well support avoid heart disease.

Alpha lipoic acid might be simply absorbed into the blood stream, and is found in vegetables and meats.

Many alpha lipoic acid medical reports have focused around buy clomid online without a prescription the rewards to folks struggling with diabetes, in certain all those men and women whose modest blood vessels are already damaged by high amounts of glucose inside the blood stream for an extended period of time, a situation known as diabetic distal symmetric polyneuropathy or diabetic neuropathy.

If you concluded that the article is intriguing you may also wish to be knowing about Benefits Of Alpha Lipoic Acids and also Alpha Lipoic Acid Side Effects.